strychnine


strychnidin-10-one; λ-strychnine; strychnine
Links:🌍 Wikipedia, 📏 NIST, 🕷 ChemSpider, 📖 PubMed
MeSH:Central Nervous System Agents; Central Nervous System Stimulants; Glycine Agents; Neurotransmitter Agents; Noxae; Poisons
CAS RN:[57-24-9]
Formula:C21H22N2O2; 334.42 g/mol
InChiKey:QMGVPVSNSZLJIA-UHFFFAOYSA-N
SMILES:O=C1CC2OCC=C3CN4CCC56C4CC3C2C5N1c7ccccc67
Molecular structure of strychnine
Pharmaceutical use:stimulant
Toxicology (LD50):3.000 mg/Kg (cat, iv); 3.000 mg/Kg(cat, or); 3.000 mg/Kg(cat, sc); 0.00 mg/Kg(chicken, sc); 3.000 mg/Kg(dog, iv); 3.000 mg/Kg(dog, or); 2.00 mg/Kg(dog, or); 3.000 mg/Kg(dog, sc); 3.00 mg/Kg(frog, sc); 1.00 mg/Kg(guinea~pig, sc); 2.000 mg/Kg(mouse, sc); 11.00 mg/Kg(pigeon, or); 3.00 mg/Kg(pigeon, sc); 3.000 mg/Kg(rabbit, iv); 14.0 mg/Kg(rabbit, or); 3.000 mg/Kg(rabbit, sc); 0.00 mg/Kg(rat, im); 6.00 mg/Kg(rat, im); 2.00 mg/Kg(rat, ip); 3.00 mg/Kg(rat, ip); 2.00 mg/Kg(rat, iv); 6.00 mg/Kg(rat, or); 17.0 mg/Kg(rat, or); 0.00 mg/Kg(rat, sc)
Melting point:280 °C
Log10 partition octanol / water:1.93
1g dissolves in:
5.00g aniline;    9.76g trichloromethane;    28.57g 1,2,3-propanetriol;    58.82g diethylamine;    66.67g pyridine;    120.05g ethanol;    129.87g benzene;    142.86g piperidine;    181.82g pentanol;    204.08g methanol;    400.00g 1,2,3-propanetriol;    454.55g tetrachloromethane;    507.61g ethyl acetate;    2,325.58g diethyl ether;    8,000.00g water;    10,752.69g hexane

Isomers

(+)-2,2'-isopropylidenebis[(4R)-4-phenyl-2-oxazoline]
Molecular structure of (+)-2,2'-isopropylidenebis[(4R)-4-phenyl-2-oxazoline]
(-)-2,2'-isopropylidenebis[(4S)-4-phenyl-2-oxazoline]
Molecular structure of (-)-2,2'-isopropylidenebis[(4S)-4-phenyl-2-oxazoline]
isostrychnine
Molecular structure of isostrychnine
strychnine
Molecular structure of strychnine