Solvent classification acc. Snyder

Solvent groups

Common laboratory solvents can be placed in groups with similar chromatographic properties. The classification below is due to Snyder.

Solvent groups (Solvent strength ε⁰ in parenthesis)
Group 0
	cyclohexane (-0.2)
	cyclopentane
	pentane (0.00)
	hexane (0.01)
	heptane (0.01)
	isooctane (0.01)
	petroleum ether
	1,1,2-trichlorotrifluoroethane
Group 1
	diethyl ether (0.38)
	methyl t-butyl ether
	diisopropyl ether
	dibutyl ether
	tetramethylguanidine
Group 2
	methanol (0.95)
	ethanol (0.88)
	n-propanol
	isopropanol (0.82)
	n-butanol
	isobutanol
	tert-butanol
	isopentanol
	octanol
Group 3
	N,N-dimethylacetamide
	N,N-dimethylformamide
	N-methylpyrrolidone
	pyridine
	dimethyl sulfoxide (0.75)
	2-methoxyethanol
	tetrahydrofuran (0.57)
Group 4
	acetic acid
	formamide
	benzyl alcohol
Group 5
	n-butyl chloride
	dichloromethane
	ethylene chloride
	tricresyl phosphate
Group 6
	acetone (0.56)
	acetonitrile (0.65)
	ethyl acetate (0.58)
	butyl acetate
	1,4-dioxane (0.56)
	glyme
	methyl ethyl ketone
	methyl isoamyl ketone
	methyl isobutyl ketone
	methyl n-propyl ketone
	propylene carbonate
	aniline
	nitromethane
Group 7
	benzene
	toluene (0.29)
	o-xylene
	nitrobenzene
	chlorobenzene
	1,2-dichlorobenzene
	1,2,4-trichlorobenzene
	diphenyl ether
Group 8
	m-cresol
	chloroform (0.40)
	dodecafluoroheptane
	water (1.00)